Mri Atlas

An MRI atlas is a standardized, three-dimensional map of anatomical structures created from magnetic resonance imaging data, providing a common reference for locating and comparing brain regions. MRI measures signals from hydrogen nuclei in a magnetic field, while computational registration aligns individual scans to a template and image contrasts distinguish tissue properties. In behavioral neuroscience, an MRI atlas supports the localization of lesions, circuits, and region-specific differences associated with behavior, helping researchers compare subjects, quantify brain structure, and relate neural variation to learning, movement, emotion, or disease. It also improves reproducibility across experiments and laboratories.

Mri Atlas - Related Videos

Research

JoVE EoE - Neuroimaging

Developing a Cerebral Blood Flow Atlas for Blood Flow Mapping

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2025

Source: Tan, Z., et al., Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling. J. Vis. Exp. (2024).This video demonstrates the method to construct a cerebral blood flow atlas by integrating magnetic resonance imaging or MRI-arterial spin labeling data with segmented brain regions, visualizing blood flow patterns, and quantifying flow levels across functional areas.

Research

JoVE Journal - Medicine

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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2024

This study integrated magnetic resonance imaging- arterial spin labeling images to derive cerebral blood flow (CBF) atlas for cerebral functional regions. Comparing typical healthy and chronic cerebral ischemia CBF atlases revealed significant differences in regional CBF distributions, enabling rapid, noninvasive assessments of functional CBF to assist in diagnosis and evaluate therapeutics.

Research

JoVE Journal - Biology
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Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas

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Cited by 202 •

2012

Tissue microarrays allows for an efficient method to gain concurrent information from a multitude of tissues. Representative parts of tissues are assembled into a single paraffin block. Sections from the block are used for immunohistochemistry and analysis of protein expression patterns. Digital scanning generates corresponding images for distribution of data.

Research

JoVE Journal - Neuroscience
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Optogenetic Functional MRI

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Cited by 15 •

2016

This protocol describes the steps and data analysis required to successfully perform optogenetic functional magnetic resonance imaging (ofMRI). ofMRI is a novel technique that combines high-field fMRI readout with optogenetic stimulation, allowing for cell type-specific mapping of functional neural circuits and their dynamics across the whole living brain.

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

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Cited by 31 •

2015

Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.

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