Axial Trapping

Axial trapping is the confinement of a microscopic object along the direction of a focused field, most commonly the optical axis of a laser beam. In optical tweezers, a high-numerical-aperture objective creates a steep intensity gradient that generates a gradient force toward the focus; stable trapping occurs when this restoring force balances the beam’s radiation pressure and other disturbances. In bioengineering, axial trapping helps position cells, microorganisms, biomolecules, and synthetic particles without physical contact. It supports precise manipulation, force measurements, assembly of microscale structures, and studies of cellular mechanics and interactions in controlled laboratory environments.

Axial Trapping - Related Videos

Research

JoVE Journal - Bioengineering

Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers

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Cited by 5 •

2011

We illustrate the use of a constant force axial optical tweezers to explore the mechanical properties of short DNA molecules. By stretching DNA axially, we minimize steric hindrances and artifacts arising in conventional lateral manipulation, allowing us to study DNA molecules as short as ~100 nm.

Education

JoVE Core - Anatomy and Physiology

Axial and Appendicular Muscles

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2024

Skeletal muscles, the key players in our body's movement, can be classified into two groups based on their location and function: axial muscles and appendicular muscles. These classifications reflect the primary roles the muscles play in the body's structure and movement. Axial Muscles Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and play a...

Social Traps

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2020

Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned more cows, the larger...

Research

JoVE Journal - Medicine
Free Sample

Method to Measure Tone of Axial and Proximal Muscle

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Cited by 5 •

2011

We have developed a device (Twister) to study the regulation of tonic muscle activity during active postural maintenance. Twister measures torsional resistance and muscular responses in standing subjects during twisting of the body axis. The device can be flexibly configured to study various aspects of tonic control across the neck, trunk, and/or hips.

Research

JoVE Journal - Engineering
Free Sample

Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps

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Cited by 19 •

2017

This paper presents a microfabrication methodology for surface ion traps, as well as a detailed experimental procedure for trapping ytterbium ions in a room-temperature environment.

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