Implant Surface Topography

Implant surface topography is the three-dimensional arrangement of features, roughness, and texture on an implant, and it helps determine how the material interacts with surrounding biological tissues. At micro- and nanoscale dimensions, surface geometry alters protein adsorption, wettability, and the physical cues available to adherent cells, influencing attachment, spreading, proliferation, and differentiation after implantation. In bioengineering, researchers tune topography through machining, coating, lithography, or other surface-modification methods to improve tissue integration and guide interface formation in devices such as orthopedic and dental implants. Characterizing these features supports rational implant design while balancing desired cell responses with risks such as bacterial attachment and inflammation.

Implant Surface Topography - Related Videos

Research

JoVE Journal - Engineering
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Laser Micromachining for Polymer Surface Topography Design

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2025

A method for imposing surface topography of light-absorbing composite polymer materials, particularly magnetoactive elastomers (MAEs), by using laser micromachining is presented. This method enables large flexibility in topographical designs and rapid prototyping. An example of structuring MAE surfaces, characterization, and their response to the external magnetic field is demonstrated.

Research

JoVE Journal - Medicine

Pilot In Vitro Study to Assess Cleaning Ability and Effects of Different Decontamination Methods on Implant Surfaces

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2025

The present pilot in vitro study aimed to evaluate the cleaning efficacy of three different decontamination tools and possible surface alterations following treatment, using permanent red ink to mimic the presence of oral biofilm.

Education

JoVE Core - Civil Engineering

Methods of Obtaining Topography

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2025

Topography involves measuring and mapping land elevations, natural features, and artificial structures to create accurate representations of the terrain. Topographic surveying relies on traditional and modern methods, each with distinct advantages and limitations.Traditional Surveying Methods:Transit stadia surveys and plane table surveys were widely used traditional surveying methods. These techniques relied on instruments like theodolites and stadia rods for measuring distances and angles,...

Polarization and Characterization of M1 and M2 Human Monocyte-Derived Macrophages on Implant Surfaces

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Cited by 2 •

2024

Here, we present a detailed protocol for assessing the immunomodulatory potential of implant surfaces in vitro, aiming to improve the reliability and reproducibility of current protocols and promoting further research. Secretory cytokine profiles, mRNA expression, and cell surface markers were monitored using blood monocyte-derived macrophages to investigate macrophage polarization cultivated on titanium.

A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation

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Cited by 21 •

2017

Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.

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