Polystyrene Nanoparticles

Polystyrene nanoparticles are nanoscale particles made from the synthetic polymer polystyrene, valued for their controllable size, large surface area, and tunable surface chemistry. In bioengineering, their behavior depends on particle size, surface charge, and functional groups, which govern colloidal stability, biomolecule adsorption, and interactions with cells and tissues. Researchers modify these surfaces or incorporate cargo to create model systems for studying nanoparticle uptake, biosensing platforms, and carriers for imaging or therapeutic agents. Their reproducible properties support controlled experiments in drug delivery and tissue engineering while helping assess how engineered materials move through biological environments and influence cellular responses.

Polystyrene Nanoparticles - Related Videos

Research

JoVE Journal - Chemistry

Using Polystyrene-block-poly(acrylic acid)-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization

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Cited by 1 •

2015

We report protocols for “polymerizing” various types of polymer-encapsulated metal nanoparticles into long chains of “homo-“ and “co-polymers”.

Research

JoVE Journal - Engineering
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Optical Trapping of Nanoparticles

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Cited by 7 •

2013

The following setup approach details low power optical trapping of dielectric nanoparticles using a double-nanohole in metal film.

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

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Cited by 5 •

2018

A procedure for the synthesis of polystyrene-grafted multiwalled carbon nanotubes using successive chemical modification steps to selectively introduce the polymer chains to the sidewalls and their self-assembly via anisotropic patchiness is presented.

Research

JoVE Journal - Bioengineering

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

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Cited by 1 •

2023

We introduce four methods to evaluate the antimicrobial activities of nanoparticles and nanostructured surfaces using in vitro techniques. These methods can be adapted to study the interactions of different nanoparticles and nanostructured surfaces with a broad range of microbial species.

Harmonic Nanoparticles for Regenerative Research

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Cited by 1 •

2014

Protocol details are provided for in vitro labeling human embryonic stem cells with second harmonic generating nanoparticles. Methodologies for hESC investigation by multi-photon microscopy and their differentiation into cardiac clusters are also presented.

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