Surgical Bypass Technique
Surgical Bypass Technique - Related Videos
05:25
Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
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Cited by 8 •
2023
This study presents a surgical porcine model of chronic myocardial ischemia due to progressive coronary artery stenosis, resulting in impaired cardiac function without infarction. Following ischemia, animals undergo off-pump coronary artery bypass graft with epicardial placement of stem cells-derived exosomes-laden collagen patch. This adjunctive therapy improves myocardial function and recovery.
08:08
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
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Cited by 8 •
2017
This paper describes how to perform cardiopulmonary bypass in mice. This novel model will facilitate the investigation of the molecular mechanisms involved in organ damage.
05:18
Roux-en-Y Gastric Bypass Procedure: A Bariatric Surgical Procedure for Gastric Resectioning in Murine Model
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2025
This video describes a bariatric surgery-Roux-en-Y procedure. This involves the cutting of the jejunum- the middle portion of the intestine- to generate two intestinal limbs. The biliary limb is attached to the existing intestinal loop and the alimentary limb is attached to the stomach, creating a gastric bypass. The gastric bypass created here helps to decrease the nutrient uptake and efficiently reduces body weight.
07:37
Roux-en-Y Gastric Bypass Operation in Rats
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Cited by 48 •
2012
Numerous studies using gastric bypass rat models have been recently conducted to uncover the underlying physiological mechanisms of Roux-en-Y gastric bypass operations. This article aims to demonstrate and discuss the technical and experimental details of our published gastric bypass rat model to understand advantages and limitations of this experimental tool.
10:38
A Modified Surgical Technique for Kidney Transplantation in Mice
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Cited by 3 •
2022
This protocol presents a new surgical technique of mouse kidney transplantation focusing on a modified arterial anastomosis strategy. A vascular suture technique including a simple and safer ureter-bladder anastomosis method is also presented. These modifications shorten the operation time and improve the success rate of the mouse kidney transplantation procedure.
FAQs
A pressure gradient provides the driving force for transport through the newly connected route. The bypass must therefore preserve a pathway in which pressure can move blood or another body fluid across the alternate connection. This principle links operative design with engineering analysis, because graft geometry and connection quality affect whether the intended route can support directed flow.
These components provide different structural options for forming the alternate pathway. A graft or conduit can supply an engineered segment, while a connected native vessel uses existing anatomy. The selected configuration must be integrated at its junctions so the route remains continuous. In bioengineering, these options create models for comparing material and structural performance.
Junctions connect the bypass component to the surrounding anatomy and establish continuity between the original and alternate routes. Their secure formation is essential because the pressure gradient can drive transport only through a connected pathway. For engineered systems, junction design is therefore relevant to evaluating how a graft or conduit functions within repaired anatomy.
Key considerations include biomaterials, scaffold architecture, surface compatibility, and mechanical performance. Biomaterials and scaffold structure define the engineered graft or conduit, while surface compatibility and mechanical behavior help characterize how it functions as part of a fluid-handling system. Evaluating these properties supports development of implants intended for vascular repair or other bypass applications.
Operative planning establishes how the alternate route will be integrated with damaged anatomy, while engineered graft design addresses the properties of the replacement segment. Considering both elements connects the practical procedure with material and structural evaluation. This combined approach helps bioengineering studies examine whether a proposed graft configuration is suitable for repair or implantation.
It is relevant when researchers need to study vascular systems, fluid-handling pathways, or engineered implants that restore transport around damaged anatomy. Bypass models provide a practical setting for examining graft design and mechanical performance alongside operative considerations. They also support research directed at circulatory disease, anatomical repair, and the development of more durable implants.
Bypass models can support evaluation of biomaterials, scaffold architecture, surface compatibility, and mechanical performance in a functional repair context. Rather than assessing an engineered component in isolation, the model places it within a redirected transport pathway. This context helps guide the design of grafts and implants for vascular applications and other body-fluid systems.