Tissue Weld Strength

Tissue weld strength is the mechanical integrity of a fused biological tissue interface and indicates how well a weld withstands tension, pressure, or shear after joining. In bioengineering, welding typically applies localized energy, such as laser or electrical energy, to heat tissue, alter collagen and other structural proteins, and create a continuous bond as the region cools and remodels. Researchers assess weld strength through tensile, burst-pressure, or shear testing while considering factors such as energy dose, tissue type, hydration, and healing time. These measurements guide the development of minimally invasive surgical tools, wound-closure methods, and tissue-engineering strategies that aim to improve repair reliability and reduce sutures or staples.

Tissue Weld Strength - Related Videos

Research

JoVE Journal - Engineering

Ultrasonic Welding of Thermoplastic Composite Coupons for Mechanical Characterization of Welded Joints through Single Lap Shear Testing

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Cited by 4 •

2016

A straightforward procedure for ultrasonic welding of thermoplastic composite coupons for basic mechanical testing is described. Key characteristics of this ultrasonic welding process are the use of flat energy directors for simplified process preparation and the use of process data for the fast definition of optimum processing conditions.

Research

JoVE Journal - Engineering
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Surrogate Model Development for Digital Experiments in Welding

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Cited by 4 •

2025

This protocol outlines a general workflow for constructing an artificial neural network for welding simulation using datasets generated automatically through Python scripts with macro functions. The workflow is validated against a benchmark case involving single-pass, straight-line welding. The surrogate model's predictive accuracy shows a strong agreement with finite element simulations.

Research

JoVE Journal - Medicine
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Measuring the Strength of Mice

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Cited by 283 •

2013

Deficits in muscular strength occur in many clinical conditions such as motor neuron disease. The inverted screen and weight lifting tests described here measure strength in mice almost exclusively, with minimal influence of factors such as coordination.

Automatic Laser-based Geometry Capture for Finite Element Analysis of Weld Beads

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2025

A process is described for acquiring near-real-time metrology of weld beads and prepare the resulting geometry automatically for finite element analysis.

Education

JoVE Science Education - Engineering

Tensile Strength of Resorbable Biomaterials

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2023

Source: Peiman Shahbeigi-Roodposhti and Sina Shahbazmohamadi, Biomedical Engineering Department, University of Connecticut, Storrs, Connecticut For over 4000 years, sutures have been used as a medical intervention. The earliest records indicate linen was the biomaterial of choice. Catgut, which is still in use today, was reportedly used to treat gladiators around 150 AD. Today, there are numerous materials being used for sutures. Sutures are classified by their composition (natural or...

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