Autosampler System

An autosampler system is an automated instrument that transfers samples into an analytical device, reducing manual handling and improving measurement consistency. It uses a programmed sequence to position vials or containers, aspirate a defined volume with a probe or syringe, and introduce the sample into a separation or detection system under controlled timing and operating conditions. In chemistry, autosampler systems support high-throughput workflows in techniques such as chromatography and spectroscopy, enabling reproducible injections, reduced contamination risk, and efficient analysis of complex sample sets.

Autosampler System - Related Videos

Research

JoVE Journal - Environment

Metabolomic Analysis of Barley by Gas Chromatography/Mass Spectrometry

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Cited by 1 •

2024

A method for metabolomic analysis of barley is presented. The method entails fractionation and derivatization of metabolites and analysis thereof by gas chromatography/mass spectrometry (GC/MS). Metabolomic analysis can be used to determine the effect of intercropping and drought stress on the grain.

Research

JoVE Journal - Biology

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome

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2023

Caenorhabditis elegans is a powerful model to examine the molecular determinants driving host-microbiome interactions. We present a high throughput pipeline profiling the single animal levels of gut microbiome colonization together with key aspects of the C. elegans physiology.

Surface Plasmon Resonance to Study Biomolecular Interactions Using a Sensor Chip

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2025

This video describes the surface plasmon resonance, or SPR, technique for studying the interaction between two molecules using a sensor chip. The change in resonance angle and the intensity of the reflected light are detected as a function of the association and dissociation of two molecules, and this provides information about the interactions between the two molecules.

Research

JoVE Journal - Biology
Free Sample

Single-Cell Proteomics Preparation for Mass Spectrometry Analysis Using Freeze-Heat Lysis and an Isobaric Carrier

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Cited by 10 •

2022

In this protocol, we describe how to prepare mammalian cells for single-cell proteomics analysis via mass spectrometry using commercially available reagents and equipment, with options for both manual and automatic pipetting.

Liquid Chromatography Coupled to Refractive Index or Mass Spectrometric Detection for Metabolite Profiling in Lysate-based Cell-free Systems

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Cited by 6 •

2021

The protocols describe high-performance liquid chromatography methods coupled to refractive index or mass spectrometric detection for studying metabolic reactions in complex lysate-based cell-free systems.

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