Standard Reference Materials
Standard Reference Materials - Related Videos
01:23
Reference & Citation Tools in Practice
0 Views •
2026
Citations play a key role in academic writing by documenting the evidence that supports scholarly claims. Beyond giving credit to original authors, they show engagement with existing research and strengthen the credibility of an argument. Effective citation practices are central to research literacy because they reflect a writer’s ability to locate, evaluate, and integrate reliable sources into their work. Digital Tools for Citation Management Advances in digital technology have simplified the...
07:22
Standardized Method for Measuring Collection Efficiency from Wipe-sampling of Trace Explosives
0 Views •
Cited by 7 •
2017
Optimized sampling protocols and the development of new wipe materials can be facilitated by standardized measurements of collection efficiency from wipe-sampling. Our approach for sampling trace explosives uses an automated device to control speed, force, and distance during wipe-sampling followed by extraction of collected explosives.
10:16
Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
0 Views •
Cited by 2 •
2015
The goal of this video is to demonstrate how to perform automated DNA extraction from formalin-fixed paraffin-embedded (FFPE) reference standard cell lines and digital droplet PCR (ddPCR) analysis to detect rare mutations in a clinical setting. Detecting mutations in FFPE samples demonstrates the clinical utility of ddPCR in FFPE samples.
10:36
Advanced Experimental Methods for Low-temperature Magnetotransport Measurement of Novel Materials
0 Views •
Cited by 2 •
2016
We describe the methodology of mechanical exfoliation and deposition of flakes of novel materials with micron-sized dimensions onto substrate, fabrication of experimental device structures for transport experimentation, and the magnetotransport measurement in a dry helium close-cycle cryostat at temperatures down to 0.300 K and magnetic fields up to 12 T.
16:11
Implementation of a Reference Interferometer for Nanodetection
0 Views •
2014
A reference interferometer technique, which is designed to remove undesirable laser jitter noise for nanodetection, is utilized for probing an ultra-high quality factor microcavity. Instructions for assembly, setup, and data acquisition are provided, alongside the measurement process for specifying the cavity quality factor.
FAQs
A laboratory analyzes the Standard Reference Material under the same measurement conditions used for a test sample, then compares the observed result with the certified value. Agreement supports confidence in the measurement, while a discrepancy can indicate a problem with the instrument, analytical method, or execution. This comparison provides evidence that results are accurate enough for their intended purpose.
Homogeneity means that portions taken from the material provide consistent composition, while stability helps preserve the assigned properties over time. Together, these characteristics reduce the likelihood that differences between measurements arise from the reference material itself. They therefore support meaningful comparisons among analysts, instruments, laboratories, and measurement dates.
Certified values provide a documented reference point against which laboratory measurements can be evaluated. When analysts use the same type of benchmark, results can be interpreted more consistently across instruments, personnel, and time. This connection strengthens traceability, meaning the measurement can be related to an established reference, and improves comparability between otherwise separate analytical results.
Results obtained from an SRM help laboratories evaluate how closely a measured value agrees with its certified value. That evidence contributes to judging measurement quality and estimating uncertainty, which describes the expected range of doubt around a result. Used with method validation and quality control, the comparison helps determine whether an analytical procedure is fit for purpose.
The laboratory selects an SRM relevant to the property being measured, analyzes it alongside test samples, and compares the measured result with the certified value. Analysts then examine the agreement to assess instrument performance, method validity, or quality-control status. Documented homogeneity and stability make the comparison more defensible when interpreting results across repeated analyses.
The purpose determines how the material is used. An SRM can support instrument calibration, test whether an analytical method produces reliable results, or monitor ongoing quality control. In each case, the certified value supplies a benchmark for evaluating performance. This makes the approach useful when laboratories need evidence that measurements are accurate, reproducible, and fit for purpose.
SRMs support a broad range of chemical measurements, including elemental analysis, environmental testing, pharmaceutical analysis, and materials characterization. In these settings, laboratories can compare measured properties with certified values to evaluate analytical performance. The resulting evidence helps researchers and testing laboratories interpret data consistently and assess whether results can be compared across instruments, analysts, or time.