Active Cantilever Arrays

Active cantilever arrays are engineered assemblies of miniature, flexible beams that combine sensing with controlled mechanical actuation, enabling many measurements or operations in parallel. Each cantilever responds to a stimulus through bending, vibration, or resonance, while integrated piezoelectric, electrostatic, or thermal elements can drive its motion; changes in deflection or resonant frequency provide measurable signals. In engineering, these arrays support chemical and biological detection, force and mass measurement, microfluidic control, and scanning or positioning systems. Their parallel architecture increases throughput and spatial resolution, while individual beam control enables selective analysis, adaptive sensing, and compact lab-on-a-chip technologies.

Active Cantilever Arrays - Related Videos

Research

JoVE Journal - Engineering

Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays for High-Throughput Large-Scale Sample Inspection

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Cited by 5 •

2023

Large-scale sample inspection with nanoscale resolution has a wide range of applications, especially for nanofabricated semiconductor wafers. Atomic force microscopes can be a great tool for this purpose, but are limited by their imaging speed. This work utilizes parallel active cantilever arrays in AFMs to enable high-throughput and large-scale inspections.

Cantilever Bending of Murine Femoral Necks

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2022

The present protocol describes the development of a reproducible testing platform for murine femoral necks in a cantilever bending set-up. Custom 3D printed guides were used to consistently and rigidly fix the femurs in optimal alignment.

Measuring the Electrophysiological Activity of Neuronal Networks Using Micro-Electrode Arrays

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2025

The video demonstrates how to use a microelectrode array (MEA) to record the electrophysiological activity of neurons derived from human induced pluripotent stem cells (hiPSCs). Electrophysiological activity from a multiwell MEA containing a neuron-astrocyte co-culture is recorded to detect action potentials from multiple neurons in the network, confirming the successful differentiation of hiPSCs into neurons.

Neural Activity Propagation in an Unfolded Hippocampal Preparation with a Penetrating Micro-electrode Array

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Cited by 2 •

2015

We have developed an in vitro unfolded hippocampus which preserves CA1-CA3 array of neurons. Combined with the penetrating micro-electrode array, neural activity can be monitored in both the longitudinal and transverse orientations. This method provides advantages over hippocampal slice preparations as the propagation in the entire hippocampus can be recorded simultaneously.

Recording Network Activity in Spinal Nociceptive Circuits Using Microelectrode Arrays

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Cited by 1 •

2022

The combined use of microelectrode array technology and 4-aminopyridine-induced chemical stimulation for investigating network-level nociceptive activity in the spinal cord dorsal horn is outlined.

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