Peak Force Quantitative Nanomechanical Property Mapping

Peak Force Quantitative Nanomechanical Property Mapping is an atomic force microscopy technique that measures and spatially maps the mechanical properties of surfaces at the nanoscale. During scanning, a probe tip approaches and retracts from each location while force-distance curves capture interactions such as deformation and adhesion; fitting these responses yields quantitative property values. In engineering, the method helps relate composition, microstructure, and processing to local stiffness and interfacial behavior in polymers, composites, coatings, and other materials. The resulting maps reveal heterogeneity and damage that bulk tests can miss, supporting failure analysis, quality control, and materials design.

Peak Force Quantitative Nanomechanical Property Mapping - Related Videos

Research

JoVE Journal - Engineering

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

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Cited by 6 •

2014

A method for investigating the structure of a protein photoreceptor using atomic force microscopy (AFM) is described in this paper. PeakForce Quantitative Nanomechanical Property Mapping (PF-QNM) reveals intact protein dimers on a mica surface.

Research

JoVE Journal - Engineering

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid

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Cited by 11 •

2022

Quantifying the contact area and force applied by an atomic force microscope (AFM) probe tip to a sample surface enables nanoscale mechanical property determination. Best practices to implement AFM cantilever-based nanoindentation in air or fluid on soft and hard samples to measure elastic modulus or other nanomechanical properties are discussed.

Research

JoVE Journal - Bioengineering
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Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps

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2025

This protocol visualizes how to prepare cryosections of murine lung tissue, perform atomic force microscopy force map experiments, and analyze the data to determine Young's modulus of the native murine pulmonary basement membrane.

Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy

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Cited by 154 •

2013

This paper demonstrates a protocol to characterize the mechanical properties of living cells by means of microindentation using an Atomic Force Microscope (AFM).

Concurrent Quantitative Conductivity and Mechanical Properties Measurements of Organic Photovoltaic Materials using AFM

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Cited by 3 •

2013

Organic photovoltaic (OPV) materials are inherently inhomogeneous at the nanometer scale. Nanoscale inhomogeneity of OPV materials affects performance of photovoltaic devices. In this paper, we describe a protocol for quantitative measurements of electrical and mechanical properties of OPV materials with sub-100 nm resolution.

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