Pressure Resistant Holder

A pressure-resistant holder is an engineered support or enclosure designed to secure an object, sample, or component while withstanding elevated internal or external pressure. It works by combining high-strength materials, reinforced geometry, and controlled load distribution so pressure forces remain within the holder’s structural limits; seals, fasteners, or locking features may also prevent movement or leakage when required. In engineering research and testing, pressure-resistant holders help maintain stable experimental conditions, protect sensitive components, and enable operation in hydraulic, pneumatic, laboratory, and industrial systems. Their design requires attention to pressure ratings, material compatibility, stress concentration, deformation, and safe failure behavior.

Pressure Resistant Holder - Related Videos

Research

JoVE Journal - Medicine

Assessing Myogenic Response and Vasoactivity In Resistance Mesenteric Arteries Using Pressure Myography

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Cited by 24 •

2015

Pressure myography is used to assess vasoactivity of small arteries that develop sustained constriction when pressurized. This manuscript provides a detailed protocol to assess in isolated segments of small mesenteric arteries from rats, vasoactivity and the effect of intraluminal pressure on vascular diameter.

Assessing Murine Resistance Artery Function Using Pressure Myography

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Cited by 18 •

2013

In pressure myography, an intact small segment of a vessel is mounted onto two small cannulas and pressurized to a suitable luminal pressure. Here, we describe the method to measure vasorelaxation response of the mouse 3rd order mesenteric arteries in c57 and sGCα1-/- mice using pressure myography.

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

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Cited by 5 •

2013

The laser heated diamond anvil cell combined with synchrotron micro-diffraction techniques allows researchers to explore the nature and properties of new phases of matter at extreme pressure and temperature (PT) conditions. Heterogeneous samples can be characterized in situ under high pressure by 2D mapping and combined powder, single-crystal and multigrain diffraction approaches.

Research

JoVE Journal - Medicine

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

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Cited by 2 •

2025

CT-guided ozone-mediated renal denervation (RDN) by injecting an O2-O3 gas mixture around lumbar ganglia reduces antihypertensive medication burden and achieves an improved home blood pressure control rate. We present a novel, simplified, unilateral, and contrast-free RDN technique that minimizes the renal artery injury in the treatment of patients with resistant hypertension (RH).

Live-Cell Imaging of Intact Ex Vivo Globes Using a Novel 3D Printed Holder

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Cited by 2 •

2022

The present work describes a novel experimental protocol that utilizes a 3D printed holder to enable high-resolution live cell imaging of enucleated globes. Through this protocol, the cellular calcium signaling activity in wounded corneal epithelium from ex vivo globes can be observed in real time.

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