Reusable Imaging Device
Reusable Imaging Device - Related Videos
11:29
Reusable Hepatic Imaging Tool: A Reusable 3D-Printed Tool for Hepatic Intravital Microscopy
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2026
This protocol introduces a cutting-edge, Reusable Hepatic Imaging Tool (RHIT) for intravital microscopy (IVM) of live mice, which enhances tissue stability for rapid and acute experiments. The RHIT's 3D-printed design offers cost-effective production, scalability, and versatility, enabling prolonged observation of metabolic processes in mice of various sizes.
10:28
Reusable Single Cell for Iterative Epigenomic Analyses
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2022
The present protocol describes a single-cell method for iterative epigenomic analyses using a reusable single cell. The reusable single cell allows analyses of multiple epigenetic marks in the same single cell and statistical validation of the results.
09:27
Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
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Cited by 16 •
2016
Presented is the protocol for co-immobilizing whole-cell biocatalysts for cofactor regeneration and improved reusability, using the production of L-xylulose as an example. The cofactor regeneration is achieved by coupling two Escherichia coli strains expressing functionally complementary enzymes; the whole-cell biocatalyst immobilization is achieved by cell encapsulation in calcium alginate beads.
07:13
Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging Modalities
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Cited by 3 •
2023
The combination of multiple imaging modalities is often necessary to gain a comprehensive understanding of pathophysiology. This approach utilizes phantoms to generate a differential transformation between the coordinate systems of two modalities, which is then applied for co-registration. This method eliminates the need for fiducials in production scans.
09:36
Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging
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Cited by 26 •
2011
A compartmentalizing microfluidic device for investigating cancer stem cell migration is described. This novel platform creates a viable cellular microenvironment and enables microscopic visualization of live cell locomotion. Highly motile cancer cells are isolated to study molecular mechanisms of aggressive infiltration, potentially leading to more effective future therapies.
FAQs
During each imaging cycle, optical components gather reflected, transmitted, or emitted signals, the illumination source supplies or conditions the relevant signal, and the detector senses it. Control electronics then convert detector output into an image. This coordinated signal path determines how spatial information is captured and makes component compatibility central to repeatable performance.
Durable materials and protective housings support repeated handling, while serviceable interfaces allow components or connections to be accessed for cleaning and maintenance. These features must be balanced against image quality and long-term performance: a design that protects the internal system but complicates servicing may undermine continued operation. Engineering decisions therefore address both physical durability and functional upkeep.
Cleanability or sterilizability affects whether the device can be prepared for another imaging cycle, while image quality determines the usefulness of the captured information. Engineering the two together helps prevent maintenance requirements from compromising optical or electronic performance. This balance is especially important when the same instrument must provide reliable images across repeated operation and handling.
The main engineering distinction is the expected operating pattern. A reusable imaging device is designed for cleaning, maintenance, and repeated imaging cycles, whereas a single-use device is not intended for that continued service. Reuse can reduce consumable waste and operating costs, but it requires attention to durability, serviceable construction, cleanability, and sustained image performance.
A repeated-use workflow includes operating the device to capture an image, then cleaning and maintaining it before subsequent use. Protective housings and serviceable interfaces can support these activities by helping preserve the system and provide access for upkeep. The exact balance between cleaning, maintenance, and performance depends on the device’s engineering requirements and intended application.
Engineers should evaluate the optical components, illumination source, detector, control electronics, durable materials, protective housing, and serviceable interfaces as an integrated system. Each element contributes either to signal capture, image formation, protection, or continued operation. Evaluating them together helps balance image quality, reliability, cleanability or sterilizability, and long-term performance.
Applications include biomedical observation, industrial inspection, laboratory measurement, and environmental monitoring. These settings use the device to capture visual or other spatial information while benefiting from operation across multiple imaging cycles. The appropriate design emphasis can vary by use case, but each application depends on maintaining useful image performance alongside the practical requirements of cleaning, maintenance, and reliability.
Assessment should focus on image quality, reliability, cleanability or sterilizability, and long-term performance. These outcomes indicate whether the device continues to capture spatial information effectively while remaining suitable for repeated operation. Engineers can also consider changes in consumable waste and operating costs, since reuse is valuable only when sustained function supports those broader benefits.