Spatially-adaptive Denormalization

Spatially-adaptive denormalization is a database design strategy that selectively duplicates or co-locates related data according to where and how it is accessed, balancing query speed with storage and consistency costs. Instead of applying one schema globally, it analyzes spatial locality, such as geographic regions, partition boundaries, or distributed storage nodes, and materializes related attributes where frequent joins or remote requests occur while preserving normalization elsewhere. In engineering systems, this approach can reduce network traffic, join latency, and response time for distributed, geospatial, edge, and cloud applications. Its effectiveness depends on workload patterns, replication overhead, update coordination, and the need to keep redundant values consistent.

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Education

JoVE Science Education - Psychology

Spatial Cueing

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2023

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University Attention refers to the limited human ability to select some information for processing at the expense of other stimuli in the environment. Attention operates in all sensory modalities: vision, hearing, touch, even taste and smell. It is most often studied in the visual domain though. A common way to study visual attention is with a spatial cueing paradigm. This paradigm allows researchers to measure the consequences of focusing...

Research

JoVE Journal - Biochemistry
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Spatial Molecular Imaging of the Glycome Using Mass Spectrometry

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2025

This protocol details the key steps to enable rigorous and reproducible measurement of both glycogen and N-linked glycans using mass spectrometry imaging.

Spatially Compact Arrangement of Larval Zebrafish Sections for Spatial Transcriptomic Analysis

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2025

Here, we present a method for aligning and cryosectioning multiple Zebrafish (Danio rerio) larvae samples and collecting them on a single slide for spatial transcriptomic analysis.

Spatial Memory Testing Using Mazes

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2023

Spatial learning and memory are neurological functions that allow us to remember important details associated with our environment. Scientists test this phenomenon in rodents using different types of mazes like Morris water maze, Radial water maze, and Barnes maze. By investigating spatial memory in rodents, neurobehavioral scientists can gain valuable understanding of how these processes are altered following brain damage in humans. Here, the neurobiology behind spatial memory is briefly...

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

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2025

This article introduces a protocol for using DeepSpaceDB, a dynamic, interactive database for spatial transcriptomics, offering analysis workflows and examples to explore tissue organization and disease-related gene expression.

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