Biomarker Analysis

Biomarker analysis is the measurement and interpretation of biological indicators that reveal exposure to environmental conditions, chemical contaminants, or ecological stress. It works by detecting molecular, biochemical, cellular, or physiological changes in organisms or environmental samples and comparing these responses with appropriate baseline conditions. In environmental sciences, researchers use biomarkers to monitor pollution, assess organism health, identify early biological effects before visible damage occurs, and evaluate ecological risk. When combined with chemical measurements and field data, biomarker analysis strengthens environmental monitoring, supports remediation decisions, and helps clarify how contaminants affect organisms and ecosystems.

Biomarker Analysis - Related Videos

Education

JoVE Science Education - Environmental Sciences

An Overview of bGDGT Biomarker Analysis for Paleoclimatology

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2023

Source: Laboratory of Jeff Salacup - University of Massachusetts Amherst Throughout this series of videos, natural samples were extracted and purified in search of organic compounds, called biomarkers, that can relate information on climates and environments of the past. One of the samples analyzed was sediment. Sediments accumulate over geologic time in basins, depressions in the Earth into which sediment flows through the action of fluid (water or air), movement, and gravity. Two main types...

An Overview of Alkenone Biomarker Analysis for Paleothermometry

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2023

Source: Laboratory of Jeff Salacup - University of Massachusetts Amherst Throughout this series of videos, natural samples were extracted and purified in search of organic compounds, called biomarkers, that can relate information on climates and environments of the past. One of the samples analyzed was sediment. Sediments accumulate over geologic time in basins, depressions in the Earth into which sediment flows through the action of fluid (water or air), movement, and gravity. Two main types...

Research

JoVE Journal - Cancer Research

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

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2023

Here, a protocol is presented in which multiple bioinformatic tools are combined to study the biological functions of TMEM200A in cancer. In addition, we also experimentally validate the bioinformatics predictions.

Research

JoVE Journal - Medicine

Isolation, Characterization, and Proteomic Analysis of Plasma-Derived Extracellular Vesicles for Cardiovascular Biomarker Discovery

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Cited by 1 •

2025

This article describes a methodology for the isolation, characterization, and quantification of human plasma-derived extracellular vesicles (EV) and presents a workflow for label-free analysis of the EV proteome using liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Research

JoVE Journal - Medicine
Free Sample

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

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Cited by 29 •

2012

We describe a rat model of post traumatic stress disorder (PTSD) that reveals the persistent alterations in neuroendocrine function and the delayed long-term, exaggerated fear response, characteristic of PTSD patients. The animal model and methods described here are useful for correlating biomarkers in brain nuclei, which are mechanistic but cannot be measured in patients, with biomarkers in peripheral white blood cells, which can.

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