Leading Term

The leading term of a polynomial is the term with the highest exponent, and it determines the polynomial’s degree and much of its behavior for large values of the variable. Its coefficient and exponent reveal how the function grows, while the coefficient’s sign helps establish the end behavior of its graph. In algebra, identifying the leading term supports polynomial classification, comparison, simplification, and estimation. It also provides a foundation for asymptotic analysis, where the leading term approximates a function when lower-degree terms become relatively insignificant, making it useful in calculus, modeling, and numerical reasoning.

Leading Term - Related Videos

Research

JoVE EoE - Neuroimaging

In Vitro Calcium Imaging in Short-Term and Long-Term Rat Hippocampal Cultures

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2025

Source: Calvo-Rodríguez, et al. Fluorescence and Bioluminescence Imaging of Subcellular Ca2+ in Aged Hippocampal Neurons. J. Vis. Exp. (2015). This video demonstrates the use of fluorescence imaging to measure cytosolic calcium levels in short-term and long-term rat hippocampal cultures. By comparing young and aged neurons, it highlights how increased L-type voltage-gated calcium channel density and prolonged activation in aged neurons result in calcium overloading, a hallmark of neuronal aging.

Education

JoVE Core - Biology

Long-term Depression

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2019

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory. Calcium Ion Concentration Mechanism If over time, all...

Lead Analysis of Soil Using Atomic Absorption Spectroscopy

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2023

Source: Laboratories of Margaret Workman and Kimberly Frye - Depaul University Lead occurs naturally in soil, in levels ranging from 10-50 ppm. However, with the widespread use of lead in paint and gasoline in addition to contamination by industry, urban soils often have concentrations of lead significantly greater than background levels – up to 10,000 ppm in some places. Ongoing problems arise from the fact that lead does not biodegrade, and instead remains in the soil. Serious health risks...

Research

JoVE Journal - Biology

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

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2023

We present a step-by-step protocol for the isolation of long-term hematopoietic stem cells (LT-HSCs) and short-term HSCs (ST-HSCs) using the Hoxb5 reporter system.

Research

JoVE Journal - Neuroscience
Free Sample

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

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Cited by 92 •

2011

Here we describe methods to test C. elegans associative learning and short- and long-term associative memory. These population assays employ the worms abilities to chemotax toward volatile odorants, and form positive associations upon pairing food with the chemoattractant butanone. Increasing the number of conditioning periods induces long-term memory.

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