Bladder Dome Exposure

Bladder dome exposure is a surgical technique used to clearly visualize the upper portion of the urinary bladder during pelvic and lower abdominal procedures. It works by creating an unobstructed operative field around the bladder dome, typically through careful tissue separation, mobilization, and controlled retraction while preserving adjacent structures. This exposure helps clinicians identify bladder anatomy, assess the relationship between the bladder and nearby organs, and perform procedures with greater precision. In medicine, it supports operative planning, facilitates access to targeted areas, and contributes to safer management of conditions requiring visualization or treatment near the bladder.

Bladder Dome Exposure - Related Videos

Research

JoVE EoE - Urinary Tract Cancer

Bladder Tumor Organoid Model: A Method for Orthotopic Transplantation of Bladder Organoids into Recipient Murine Bladder

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2023

In this video, we describe the orthotopic transplantation of cultured bladder tumor organoids into the murine bladder to study the role of the organ environment on developing tumors.

Research

JoVE Journal - Cancer Research

Culture of Bladder Cancer Organoids as Precision Medicine Tools

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Cited by 4 •

2021

Patient-derived organoids (PDOs) are a powerful tool in translational cancer research, reflecting both the genetic and phenotypic heterogeneity of the disease and response to personalized anti-cancer therapies. Here, a consolidated protocol to generate human primary bladder cancer PDOs in preparation for the evaluation of phenotypic analyses and drug responses is detailed.

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

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Cited by 19 •

2014

Approximately 3-8 million people in the United States suffer from interstitial cystitis/bladder pain syndrome (IC/BPS), a debilitating condition characterized in part by pelvic pain. In order to study nervous system contributions to the condition, a physiological model of urinary bladder pain is used in mice and rats.

Mouse Bladder Wall Injection

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Cited by 30 •

2011

Mouse bladder wall injection is a useful approach to orthotopically study bladder stem cell and cancer biology. This delicate microsurgical method can be mastered with careful technique and practice.

Whole-Body Nanoparticle Aerosol Inhalation Exposures

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Cited by 51 •

2013

A whole-body nanoparticle aerosol inhalation exposure facility was constructed for nano-sized titanium dioxide (TiO2) inhalation toxicology studies. This system provides nano-TiO2 aerosol test atmospheres that have: 1) a steady mass concentration; 2) a homogenous composition free of contaminants; and 3) a stable particle size distribution during aerosol generation.

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