Short Axis Sequence
Short Axis Sequence - Related Videos
07:51
Murine Short Axis Ventricular Heart Slices for Electrophysiological Studies
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Cited by 3 •
2017
Here, we describe the preparation of viable ventricular slices from adult mice and their use for sharp electrode action potential recordings. These multicellular preparations provide a preserved in vivo like tissue structure, which makes them a valuable model for electrophysiological and pharmacological studies in vitro.
08:48
Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
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Cited by 5 •
2011
We illustrate the use of a constant force axial optical tweezers to explore the mechanical properties of short DNA molecules. By stretching DNA axially, we minimize steric hindrances and artifacts arising in conventional lateral manipulation, allowing us to study DNA molecules as short as ~100 nm.
12:08
Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
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Cited by 9 •
2021
This protocol details a comprehensive approach for the culturing, sequencing, and de novo hybrid genome assembly of urinary bacteria. It provides a reproducible procedure for the generation of complete, circular genome sequences useful in studying both chromosomal and extrachromosomal genetic elements contributing to urinary colonization, pathogenesis, and antimicrobial resistance dissemination.
01:37
Hypothalamic-Pituitary Axis
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2019
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor. What Happens During Stress In response to stress, the neurons in the hypothalamus release...
01:14
Short run
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2024
The short run is defined not by a fixed timeframe, but by the condition in which at least one input in the production process remains fixed. The input whose quantity cannot be changed is called the fixed input. The input whose quantity can be changed is called the variable input. When all inputs can be changed, the time frame becomes the long run. Typically, the fixed input is capital, such as machinery or the physical size of a production facility, which cannot be easily or quickly changed. In...
FAQs
Orientation determines what can be compared across the ventricles. By collecting cross-sectional images perpendicular to the heart’s long axis, the Short Axis Sequence presents ventricular anatomy in a consistent plane. Contiguous coverage from the base to the apex reduces gaps between levels, supporting systematic review of chamber size, wall thickness, and regional contraction.
Electrocardiographic gating links image acquisition to the cardiac cycle, allowing images to represent comparable phases of ventricular motion. This synchronization is important because apparent changes in chamber size or wall movement can otherwise reflect timing differences rather than true physiology. The resulting cine series supports assessment of ventricular function across the heartbeat.
The series supports quantitative assessment of ventricular volumes, ejection fraction, and wall thickness, while cine views show regional wall motion. Together, these measures connect chamber performance with localized abnormalities. In medicine, that combination helps evaluate ischemia, cardiomyopathy, myocardial scarring, and congenital abnormalities rather than relying on a single structural observation.
A typical short-axis acquisition uses cardiac MRI with electrocardiographic gating and collects contiguous cine slices from the ventricular base through the apex. The resulting stack is then reviewed across the cardiac cycle, allowing investigators to examine both anatomy and motion at multiple ventricular levels rather than one isolated image.
Its clinical value extends across evaluation of ventricular structure and function and assessment of suspected cardiovascular disease. The findings can contribute to identifying ischemia, cardiomyopathy, myocardial scarring, and congenital abnormalities. Because the sequence provides both measurements and regional motion information, it can support diagnostic assessment and treatment planning.
Repeated examinations can use the same base-to-apex ventricular coverage and functional measurements to follow cardiovascular disease over time. Comparing ventricular volumes, ejection fraction, wall thickness, and regional wall motion may show whether cardiac status has changed. This makes the approach relevant not only to initial assessment but also to ongoing clinical evaluation and treatment planning.