Anatomy-based Fitting

Anatomy-based fitting is the process of adapting a neuroscientific device, measurement system, or intervention to an individual’s anatomical structure rather than relying on a standard configuration. It uses anatomical landmarks or imaging data to guide the placement, alignment, and sizing of components, helping match electrodes, sensors, stimulators, or other interfaces to the relevant brain region and surrounding tissues. In neuroscience, this individualized approach can improve signal quality, targeting accuracy, comfort, and reproducibility across participants. Anatomy-based fitting therefore supports more precise neuroimaging, brain stimulation, electrophysiology, and neuroprosthetic applications while accounting for meaningful variation in human anatomy.

Anatomy-based Fitting - Related Videos

Research

JoVE Journal - Bioengineering

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

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Cited by 33 •

2015

Scaffolds capable of fitting within cranio-maxillofacial (CMF) bone defects while exhibiting osteoconductivity and bioactivity are of interest. This protocol describes the preparation of a shape memory scaffold based on polycaprolactone diacrylate (PCL-DA) using a solvent-casting particulate-leaching (SCPL) method employing a fused salt template and application of a bioactive polydopamine coating.

Education

JoVE Core - Biology

Induced-fit Model

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2019

Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon. Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical characteristics of...

Research

JoVE Journal - Medicine
Free Sample

Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example

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Cited by 1 •

2025

Here, we describe a protocol for constructing a heart model from scratch based on computed tomography and present it to medical students using three-dimensional (3D) printing and mixed reality technology to learn anatomy.

Inclusive Fitness

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2025

Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help. Inclusive fitness is an individual’s ability to pass down their genes—both through their offspring and the offspring of close relatives with shared genes. If an animal helps a close relative improve their reproductive success, this increases the animal’s...

Research

JoVE Journal - Biology
Free Sample

A Quantitative Fitness Analysis Workflow

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Cited by 25 •

2012

Quantitative Fitness Analysis (QFA) is a complementary series of experimental and computational methods for estimating microbial culture fitnesses. QFA estimates the effect of genetic mutations, drugs or other applied treatments on microbe growth. Experiments scaling from focussed analysis of single cultures to thousands of parallel cultures can be designed.

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