Brain-behavior Correlation

Brain-behavior correlation is the study of how patterns in brain structure or activity relate to observable behaviors, cognition, and emotional states. Researchers examine these relationships by comparing neural measurements, such as brain imaging or electrophysiological signals, with behavioral performance, while recognizing that correlation does not by itself establish causation. In neuroscience, this approach helps identify neural systems associated with perception, learning, memory, decision-making, and motor control. Combining brain-behavior analyses with lesion studies, stimulation, or longitudinal measurements can clarify underlying mechanisms and improve understanding of neurological and psychiatric conditions.

Brain-behavior Correlation - Related Videos

Research

JoVE Journal - Behavior
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Profiling Maternal Behavior Responses During Whole-Brain Imaging

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2025

Presented here is a video analysis pipeline that overcomes challenges in behavioral monitoring within MRI environments, allowing for the detection of uninstructed behavioral responses to external cues. This analysis will facilitate a more comprehensive understanding of evoked internal state changes and brain-wide activity.

Research

JoVE Journal - Medicine
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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

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Cited by 29 •

2012

We describe a rat model of post traumatic stress disorder (PTSD) that reveals the persistent alterations in neuroendocrine function and the delayed long-term, exaggerated fear response, characteristic of PTSD patients. The animal model and methods described here are useful for correlating biomarkers in brain nuclei, which are mechanistic but cannot be measured in patients, with biomarkers in peripheral white blood cells, which can.

Research

JoVE Journal - Neuroscience

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

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Cited by 10 •

2011

This article demonstrates an experimental design in which whole-body animated characters are used in conjunction with functional magnetic resonance imaging (fMRI) to investigate the neural correlates of observing virtual social interactions.

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

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Cited by 6 •

2011

We present a protocol that allows investigation of the neural correlates of deliberate and automatic emotion regulation, using functional magnetic resonance imaging. This protocol can be used in healthy participants, both young and older, as well as in clinical patients.

Research

JoVE Journal - Behavior
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Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

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Cited by 60 •

2014

Transcranial magnetic stimulation (TMS) is a technique for non-invasively disrupting neural information processing and measuring its effect on behavior. When TMS interferes with a task, it indicates that the stimulated brain region is necessary for normal task performance, allowing one to systematically relate brain regions to cognitive functions.

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