Injectrode Construction
Injectrode Construction - Related Videos
13:43
Fabrication of Myogenic Engineered Tissue Constructs
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Here, we demonstrate fabrication of collagen-based, tissue constructs containing skeletal myoblasts. These 3-D engineered constructs may be used to replace or repair tissues in vivo. For our purposes, we have designed these as an atrioventricular electrical conduit for the repair of complete heart block[1].
13:48
Design and Construction of an Urban Runoff Research Facility
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10:08
Construction and Setup of a Bench-scale Algal Photosynthetic Bioreactor with Temperature, Light, and pH Monitoring for Kinetic Growth Tests
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This paper describes the assembly process and operation of a bench-scale photosynthetic bioreactor that can be used, in conjunction with other methods, to estimate pertinent kinetic growth parameters. This system continuously monitors the pH, light, and temperature using sensors, a data acquisition and control unit, and open-source data acquisition software.
01:24
Bode Plots Construction
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2024
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω): It has constant gain, zeros, and poles. After normalizing the transfer function is written as: Each term in this normalized function affects the Bode plot distinctly. The term 10jω has a constant gain of 10 and zero at origin jω. Each simple...
11:11
Construction and Characterization of a Novel Vocal Fold Bioreactor
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Cited by 8 •
2014
A novel vocal fold bioreactor capable of delivering physiologically relevant, vibratory stimulation to cultured cells is constructed and characterized. This dynamic culture device, when combined with a fibrous poly(ε-caprolactone) scaffold, creates a vocal fold-mimetic environment that modulates the behaviors of mesenchymal stem cells.
FAQs
The conductive and insulating components contribute different functions within the neural interface. The conductive element provides electrical access for recording or stimulation, while the insulating, biocompatible structure supports the device and its interaction with tissue. Together, these components help the electrode maintain an electrical interface after injection and positioning within nervous tissue.
Geometry and material selection influence three practical outcomes: impedance, positional stability, and tissue compatibility. Geometry determines how the conductive interface is arranged and delivered, whereas materials affect both electrical behavior and interaction with tissue. During construction, these variables must be considered together because they jointly shape the resulting neural interface.
An injectrode can support neural recording or electrical stimulation, depending on the experimental goal. Recording uses the electrical interface to access neural activity, whereas stimulation uses that interface to deliver electrical input. The same construction principles therefore support studies that measure nervous-system signals and studies that alter neural activity through electrical intervention.
Biocompatibility matters because the electrode is positioned within nervous tissue after delivery. The insulating structure is specifically described as biocompatible, linking construction to tissue compatibility as well as electrical function. This consideration is relevant when experiments require an interface that remains usable for neural recording or stimulation after injection.
The target tissue determines which part of the nervous system the interface can address. Injectrodes may be used with peripheral nerves or the brain, allowing researchers to investigate electrical activity or stimulation in different neural settings. This range makes the intended tissue and experimental objective important considerations when selecting the device configuration.
The small delivery needle provides a route for positioning the electrode within tissue, while the compact format may reduce surgical disruption. After injection, the device must maintain its electrical interface so researchers can access neural activity or deliver stimulation. Construction therefore connects the physical delivery step with later neural measurements or interventions.
Applications include studies of circuit function, disease models, and emerging neurotechnologies. In circuit research, electrical access can support investigation of neural activity or stimulation; in disease models, the same capabilities can be applied to altered nervous systems. The compact interface format also provides a construction approach for developing less invasive neural technologies.