Mechanical Stress

Mechanical stress is the internal force distributed across a material when external loads act on it, and it describes how solids respond to compression, tension, shear, or twisting. It is calculated as force divided by the area over which the force acts, while the resulting deformation depends on material properties, geometry, and loading conditions; elastic materials recover after the load is removed, whereas excessive stress can cause yielding, fracture, or buckling. In physics and engineering, analyzing mechanical stress helps predict structural safety, select materials, interpret strain measurements, and design components that withstand forces in buildings, machines, vehicles, and biological systems.

Mechanical Stress - Related Videos

Research

JoVE Journal - Immunology and Infection

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease

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Cited by 5 •

2022

The present protocol describes the development of a Crohn's-like colitis model in rodents. Transmural inflammation leads to stenosis at the TNBS instillation site, and mechanical enlargement is observed in the segment proximal to the stenosis. These changes allow studying mechanical stress in colitis.

Research

JoVE Journal - Engineering
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A Cost-effective and Reliable Method to Predict Mechanical Stress in Single-use and Standard Pumps

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Cited by 4 •

2015

Shear stress investigations on an oil-water emulsion system result in drop breakup over the experimental time. To count drop sizes in pumping processes, the suitability of inline endoscopy was successfully demonstrated in this protocol.

Research

JoVE Journal - Medicine
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A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

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Cited by 32 •

2014

A mouse tumor model of surgical stress is used to explore how postoperative immune suppression promotes metastatic disease and to evaluate immunostimulatory perioperative therapies.

Education

JoVE Science Education - Engineering

Stress-Strain Characteristics of Aluminum

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA Aluminum is one of the most abundant materials in our lives, as it is omnipresent in everything from soda cans to airplane components. Its widespread use is relatively recent (1900AD), primarily because aluminum does not occur in its free state, but rather in combination with oxygen and other elements, often in the form of Al2O3. Aluminum was originally obtained from bauxite mineral deposits...

Modeling Social Stress

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2023

Stress negatively affects our quality of life. In particular, some individuals experience social stress when placed in a social environment that they are unfamiliar with or have difficulty adjusting to. Since it is hard to examine mechanisms of social stress in humans, modeling this condition in animals may help scientist in developing new therapies for treating this commonly encountered problem. This science education video begins by discussing the known anatomy and physiology behind stress...

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