Hidden Platform Condition

The hidden platform condition is a behavioral testing paradigm in which an animal must locate an escape platform submerged beneath opaque water, making spatial memory rather than direct visual detection essential. In the Morris water maze, animals learn the platform’s fixed location by integrating distal environmental cues, while measures such as escape latency, swim path, and search strategy indicate learning and memory performance. Neuroscience researchers use this condition to investigate hippocampal function and spatial navigation, assess the effects of brain injury or neurological disease, and evaluate how drugs or genetic changes alter memory-related behavior.

Hidden Platform Condition - Related Videos

Research

JoVE EoE - Rodent Models

The Water Maze with Platform Relocation: A Method to Assess Working Memory

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2023

In this video, we describe the Morris water maze test with platform relocation, a navigational task used to study working memory in rodents.

Research

JoVE Journal - Chemistry

Uncovering Hidden Dynamics of Natural Photonic Structures Using Holographic Imaging

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Cited by 6 •

2022

The paper is primarily focused on the combined power of optical (linear and nonlinear) and holographic methods used to reveal phenomena at the nanoscale. The results obtained from the biophotonic and oscillatory chemical reactions' studies are given as representative examples, highlighting holography's ability to reveal dynamics at a nanoscale.

Reverse Dissection and DiceCT Reveal Otherwise Hidden Data in the Evolution of the Primate Face

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Cited by 6 •

2019

Facial expressions are a mode of visual communication produced by mimetic muscles. Here, we present protocols for the novel techniques of reverse dissection and DiceCT to fully visualize and assess mimetic muscles. These combined techniques can examine both morphological and physiological aspects of mimetic musculature to determine functional aspects.

Education

JoVE Science Education - Psychology

Fear Conditioning

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2023

Fear Conditioning is a type of learning in which an association is established between a negative unpleasant event and a harmless stimulus. This leads to a fear of the harmless stimulus. This process is largely mediated by the amygdala, which is a brain region involved in emotions and stress reactions. Fear conditioning can be utilized in several ways to understand different aspects of learning and memory. This video presents an overview of the principles behind fear conditioning, discusses the...

A Robotic Platform for High-throughput Protoplast Isolation and Transformation

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Cited by 21 •

2016

A high-throughput, automated, tobacco protoplast production and transformation methodology is described. The robotic system enables massively parallel gene expression and discovery in the model BY-2 system that should be translatable to non-model crops.

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