Retractable Insertion Shuttle

A retractable insertion shuttle is a temporary support device that enables flexible neural probes to be inserted into brain tissue while minimizing deformation during placement. The shuttle provides the stiffness needed for penetration, guides the probe to a selected target, and then withdraws so the probe can remain in the tissue without a permanent rigid support. This approach is useful for deploying ultrathin or soft electrodes designed to reduce mechanical mismatch with the brain. In neuroscience, retractable shuttles support chronic neural recording and stimulation studies, improving access to delicate brain regions while helping preserve the probe’s long-term flexibility and biocompatibility.

Retractable Insertion Shuttle - Related Videos

Education

JoVE Core - Anatomy and Physiology

Clot Retraction and Fibrinolysis

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2024

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.

Research

JoVE Journal - Biology

Cargo Loading onto Kinesin Powered Molecular Shuttles

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Cited by 4 •

2010

Molecular shuttles consisting of functionalized microtubules gliding on surface-adhered kinesin motor proteins can serve as a nanoscale transport system. Here, the assembly of a typical shuttle system is described.

Research

JoVE Journal - Neuroscience

Shuttle Box Assay as an Associative Learning Tool for Cognitive Assessment in Learning and Memory Studies using Adult Zebrafish

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Cited by 6 •

2021

Learning and memory are potent metrics in studying either developmental, disease-dependent, or environmentally induced cognitive impairments. Most cognitive assessments require specialized equipment and extensive time commitments. However, the shuttle box assay is an associative learning tool that utilizes a conventional gel box for rapid and reliable assessment of adult zebrafish cognition.

Central Venous Catheter Insertion: Subclavian Vein

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations for hemodynamic monitoring, medication delivery, and blood sampling. There are three veins in the body that are accessed for central venous cannulation: the internal jugular, the subclavian, and the femoral vein. Central venous access via the subclavian vein has several advantages over other possible locations. The subclavian...

Central Venous Catheter Insertion: Femoral Vein

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2023

Source: James W Bonz, MD, Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA Central venous access is necessary in a multitude of clinical situations, including vascular access, vasopressor and caustic medication delivery, central venous pressure monitoring, volume resuscitation, total parental nutrition, hemodialysis, and frequent phlebotomy. There are three veins in the body that are accessed for central venous cannulation: the internal jugular, the subclavian, and the...

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