This study used a rat model of paraquat-induced acute lung injury to evaluate the protective effects of sesquiterpene lactones from Eupatorium lindleyanum DC. through histopathological, inflammatory, molecular, and untargeted metabolomic analyses.

evaluation-sesquiterpene-lactones-rat-model-paraquat-induced-acute

Evaluation of Sesquiterpene Lactones in a Rat Model of Paraquat-Induced Acute Lung Injury Using Untargeted Metabolomics

This study investigated the protective effects and potential mechanisms of sesquiterpene lactones from Eupatorium lindleyanum DC. (SLEL) against paraquat ...

This study demonstrates that sesquiterpene lactones from Eupatorium lindleyanum DC. (SLEL) exert significant antiinflammatory effects in xylene-induced mouse ear edema and carrageenan-induced rat paw edema models by alleviating histopathological damage, reducing cytokine release, and inhibiting NF-&#954;B signaling activation.

antiinflammatory-effects-sesquiterpene-lactones-from-eupatorium

Antiinflammatory Effects of Sesquiterpene Lactones from Eupatorium lindleyanum DC. in Rodent Models

Acute inflammation is a fundamental pathological process involved in many immune-related diseases. Eupatorium lindleyanum DC., a traditional medicinal ...

Institution - Chongqing University of Chinese Medicine

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