<p class="jove_content">This article explains how novel morphological features in cells and organoids can be quantified using the linearized compressed polar coordinates (LCPC) transform, a spatial algorithm that captures properties that traditional metrics, such as area, volume, and surface area, cannot. Best practices for shape orientation and alignment are discussed.</p>

a-shape-analysis-algorithm-quantifies-spatial-morphology-context-2d

A Shape Analysis Algorithm Quantifies Spatial Morphology and Context of 2D to 3D Cell Culture for Novel Quantitation of Phenotypes

Numerous studies have shown that the morphological phenotype of a cell or organoid correlates with its susceptibility to anti-cancer agents. However, ...

Institution - Tissue Spatial Geometrics Lab

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