<p class="jove_content">This protocol presents a rat model of contrast-induced acute kidney injury and evaluates the post-contrast administration of N-acetylcysteine and montelukast, separately and in combination. The treatment regimens were associated with less severe renal dysfunction, oxidative stress, inflammation, and histopathological injury, although combined treatment did not consistently outperform monotherapy.</p>

nephroprotective-effects-post-contrast-n-acetylcysteine-montelukast

Nephroprotective Effects of Post-contrast N-Acetylcysteine and Montelukast Treatment in a Rat Model of Contrast-induced Acute Kidney Injury

Contrast-induced acute kidney injury (CI-AKI) is an important complication of iodinated contrast exposure in which oxidative stress and inflammatory ...

Institution - Kırşehir Ahi Evran University Faculty of Medicine

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