<p class="jove_content">This protocol describes the establishment of patient-derived colon tumor organoids in co-culture with autologous lymphocytes, followed by treatment with therapeutic small molecules and immune checkpoint inhibitors to evaluate T cell reactivity and treatment efficacy.</p>

a-multimodal-framework-to-assess-patient-derived-colon-tumor

A Multimodal Framework to Assess Patient-Derived Colon Tumor Organoid&#8211;Immune Cell Co-cultures

T cells play a key role in cancer immunotherapy, and understanding their interactions with tumors is essential for developing novel immunotherapies. This ...

Institution - Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine

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