<p class="jove_content">This protocol enables the reproducible, cost-effective, and highly efficient generation of human neuromyocardial organoids containing neural crest-derived proprioceptive-biased neurons, and their application to real-time mitochondrial function monitoring and to modelling neuro-cardiac diseases, such as Friedreich&#39;s ataxia <em>in vitro</em>.</p>

generation-spontaneously-beating-neuromyocardial-organoids-with

Generation of Spontaneously Beating Neuromyocardial Organoids with Neural Crest-Derived Proprioceptive-Biased Neurons and Real-Time Respirometry

The neural crest gives rise to diverse cell types, including the proprioceptive sensory neurons that relay limb and organ position to the central nervous ...

Institution - KosBio P.C.

Articles Published in JoVE