<p class="jove_content">Here we describe a general method for random microseed matrix screening. This technique is shown to significantly increase the success rate of protein crystallization screening experiments, reduce the need for optimization, and provide a reliable supply of crystals for data collection and ligand-soaking experiments.</p>

improving-success-rate-protein-crystallization-random-microseed

Improving the Success Rate of Protein Crystallization by Random Microseed Matrix Screening

Random microseed matrix screening  (rMMS) is a protein crystallization technique in which seed crystals are added  to random screens. By increasing the ...

Institution - Douglas Instruments

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