Heart Function Imaging

Heart function imaging uses medical imaging techniques to visualize how the heart contracts, pumps blood, and responds to physiological or pathological changes. Depending on the modality, ultrasound reflections, magnetic resonance signals, or radioactive tracer distribution reveal cardiac chamber motion, valve activity, blood flow, and myocardial perfusion. In biology, these methods support the study of cardiovascular physiology, disease mechanisms, cardiac development, and treatment responses, while providing noninvasive measurements that connect heart structure with function and help researchers and clinicians evaluate changes over time.

Heart Function Imaging - Related Videos

Research

JoVE Journal - Biology

Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)

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Cited by 23 •

2016

Here, the experimental protocols are described for preparing Drosophila at different developmental stages and performing longitudinal optical imaging of Drosophila heartbeats using a custom optical coherence microscopy (OCM) system. The cardiac morphological and dynamical changes can be quantitatively characterized by analyzing the heart structural and functional parameters from OCM images.

Research

JoVE Journal - Bioengineering
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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

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Cited by 8 •

2021

This study describes a comprehensive cardiovascular magnetic resonance imaging (CMR) protocol to quantify the left ventricular functional parameters of the mouse heart. The protocol describes the acquisition, post-processing, and analysis of the CMR images as well as assessment of different cardiac functional parameters.

Viral Gene Delivery in the Mouse Heart for Evaluating Gene Effects on Heart Function

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2026

Source: Lu, A., et al. Viral Transgene Expression in Rodent Hearts and the Assessment of Cardiac Arrhythmia Risk. J. Vis. Exp. (2022)The video demonstrates a method for ultrasound-guided intramyocardial injection of a recombinant viral vector in a mouse model. This technique enables targeted gene delivery to the heart for studying the effects of transgene expression on cardiac function.

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

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2023

The present protocol describes obtaining the pressure-volume relationship through transesophageal pacing, which serves as a valuable tool in evaluating diastolic function in mouse models of heart failure.

Ex Situ Heart Perfusion: A Technique to Preserve Isolated Porcine Heart Function

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2025

This video describes an ex situ technique for preserving an isolated porcine heart by perfusing it with an oxygenated nutrient-rich perfusate solution. The technique allows the comprehensive evaluation of cardiac performance under physiological conditions.

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