Coronary Sinus Cannulation

Coronary sinus cannulation is a procedure that places a catheter into the coronary sinus, the major venous channel draining blood from the heart muscle, to enable controlled access to cardiac circulation. Typically, clinicians advance the catheter through venous access into the right atrium and guide its tip into the coronary sinus, where secure positioning allows blood sampling, pressure measurement, or infusion. In bioengineering, this approach supports retrograde delivery of cardioplegia, targeted therapeutics, and contrast agents while informing the design of catheters, sensors, and cardiac support systems. Its effectiveness depends on accurate navigation, stable placement, and controlled flow within the coronary venous anatomy.

Coronary Sinus Cannulation - Related Videos

Research

JoVE Journal - Medicine

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm

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Cited by 15 •

2021

Myocardial lactate production (coronary arterial-venous difference in serum lactate level) during coronary spasm provocation testing is considered as a highly sensitive marker that reflects acetylcholine-induced myocardial ischemia due to microvascular spasm. This article presents the procedures to assess myocardial lactate production for the diagnosis of coronary microvascular spasm.

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

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Cited by 7 •

2017

Surgical correction of ALCAPA is highly recommended, regardless of age or the degree of intercoronary collateralization. This protocol presents a technique for the direct re-implantation of adult-type ALCAPA into the aorta to re-establish the dual-coronary perfusion. Whenever feasible, direct re-implantation is preferred to other surgical correction techniques.

Education

JoVE Science Education - Clinical Skills

Nose, Sinuses, Oral Cavity and Pharynx Exam

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2023

Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA This video provides an overview of sinus, nose, and throat examinations. The demonstration begins with a brief overview of the anatomy of the region. The upper third of the nose is bony, and the bottom two-thirds are cartilaginous. Air entering the nares passes through the nasal vestibules and into the narrow passageway between the nasal septum...

Intraduodenal Cannulation in a Rat Model for Immunopathology Studies

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2025

This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.

Coronary Angiography During Ex-Situ Heart Perfusion in a Porcine Model

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2024

Screening for coronary artery disease could increase the procurement of donor hearts with extended criteria. A protocol for performing reproducible coronary angiography during ex-situ heart perfusion is described herein in a porcine model.

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